Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors

Suazo, K. F., Mishra, V., Maity, S., Auger, S. A., Justyna, K., Petre, A. M., Ottoboni, L., Ongaro, J., Corti, S. P., Lotti, F., Przedborski, S., & Distefano, M. D. (2024). Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors. Bioorganic Chemistry, 147, 107365. https://doi.org/10.1016/j.bioorg.2024.107365
Authors:
Kiall F Suazo
Vartika Mishra
Sanjay Maity
Shelby A Auger
Katarzyna Justyna
Alexandru M Petre
Linda Ottoboni
Jessica Ongaro
Stefania P Corti
Francesco Lotti
Serge Przedborski
Mark D Distefano
Affiliated Authors:
Vartika Mishra
Francesco Lotti
Serge Przedborski
Columbia Affiliation:
Subjects:
Astrocytes (MeSH)
Protein Prenylation (MeSH)
Alkynes (MeSH)
Motor Neurons (MeSH)
Author Keywords:
prenylation
farnesylation
geranylgeranylation
metabolic labeling
proteomics
synthetic probe
click chemistry
elink
Publication Type:
Article
Unique ID:
10.1016/j.bioorg.2024.107365
PMID:
38636436
DOI:
10.1016/j.bioorg.2024.107365
Journal:
Bioorganic Chemistry
Publication Date:
Data Source:
PubMed
Source Link:
View PubMed Record
View Scopus Record
View Web of Science Record

Record Created: