CDKN2A-p16 Deletion and Activated KRASG12D Drive Barrett's-Like Gland Hyperplasia-Metaplasia and Synergize in the Development of Dysplasia Precancer Lesions

Sun, J., Sepulveda, J. L., Komissarova, E. V., Hills, C., Seckar, T. D., LeFevre, N. M., Simonyan, H., Young, C., Su, G., Del Portillo, A., Wang, T. C., & Sepulveda, A. R. (2024). CDKN2A-p16 Deletion and Activated KRASG12D Drive Barrett’s-Like Gland Hyperplasia-Metaplasia and Synergize in the Development of Dysplasia Precancer Lesions. Cellular and Molecular Gastroenterology and Hepatology, 17(5), 769–784. https://doi.org/10.1016/j.jcmgh.2024.01.014
Authors:
Jing Sun
Jorge L Sepulveda
Elena V Komissarova
Caitlin Hills
Tyler D Seckar
Narine M LeFevre
Hayk Simonyan
Colin Young
Gloria Su
Armando Del Portillo
Timothy C Wang
Antonia R Sepulveda
Affiliated Authors:
Gloria Su
Armando Del Portillo
Timothy C Wang
Author Keywords:
barrett's metaplasia
cdkn2a-p16
kras
dysplasia
esophageal adenocarcinoma
murine genetic models
3d organoids
transcriptomics
barrett's metaplasia, cdkn2a-p16, kras, dysplasia, esophageal adenocarcinoma, murine genetic models, 3d organoids, transcriptomics
Publication Type:
Article
Unique ID:
10.1016/j.jcmgh.2024.01.014
PMID:
Journal:
Publication Date:
Data Source:
PubMed

Record Created: